Synthesis of an Optically Active C1‐Symmetric Al(salalen) Complex and Its Application to the Catalytic Hydrophosphonylation of Aldehydes

Angewandte Chemie International EditionVolume 44, Issue 29 p. 4600-4602 Communication Synthesis of an Optically Active C1-Symmetric Al(salalen) Complex and Its Application to the Catalytic Hydrophosphonylation of Aldehydes† Bunnai Saito, Bunnai Saito Department of Chemistry, Faculty of Science, Graduate School, Kyushu University, 33, Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan, Fax: (+81) 92-642-2607Search for more papers by this authorTsutomu Katsuki Prof., Tsutomu Katsuki Prof. [email protected] Department of Chemistry, Faculty of Science, Graduate School, Kyushu University, 33, Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan, Fax: (+81) 92-642-2607Search for more papers by this author Bunnai Saito, Bunnai Saito Department of Chemistry, Faculty of Science, Graduate School, Kyushu University, 33, Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan, Fax: (+81) 92-642-2607Search for more papers by this authorTsutomu Katsuki Prof., Tsutomu Katsuki Prof. [email protected] Department of Chemistry, Faculty of Science, Graduate School, Kyushu University, 33, Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan, Fax: (+81) 92-642-2607Search for more papers by this author First published: 08 July 2005 https://doi.org/10.1002/anie.200501008Citations: 125 † Financial support was provided by CREST of the Japan Science and Technology Agency. B.S. is grateful for research fellowships from the Japan Society for the Promotion of Science for Young Scientists. Salalen refers to an achiral hybrid salan/salen tetradentate ligand. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Graphical Abstract Quite universally: The chiral trigonal-bipyramidal Al(salalen) complex 1 was synthesized and found to be an efficient catalyst for enantioselective hydrophosphonylation of various aldehydes with dimethyl phosphite (see scheme). 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