Direct Renin Inhibitors as a New Therapy for Hypertension

ADVERTISEMENT RETURN TO ISSUEPREVPerspectiveNEXTDirect Renin Inhibitors as a New Therapy for HypertensionRandy L. Webb†, Nikolaus Schiering‡, Richard Sedrani‡, and Jürgen Maibaum*‡View Author Information† Novartis Pharmaceuticals Corp., Institutes for BioMedical Research, East Hanover, New Jersey‡ Novartis Pharma AG, Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland*To whom correspondence should be addressed. Phone: +41-61-6965560. Fax: +41-61-6967155. E-mail: [email protected]Cite this: J. Med. Chem. 2010, 53, 21, 7490–7520Publication Date (Web):August 23, 2010Publication History Received21 December 2009Published online23 August 2010Published inissue 11 November 2010https://pubs.acs.org/doi/10.1021/jm901885shttps://doi.org/10.1021/jm901885sreview-articleACS PublicationsCopyright © 2010 American Chemical SocietyRequest reuse permissionsArticle Views3740Altmetric-Citations65LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Inhibitors,Monomers,Peptides and proteins,Peptidomimetics,Rodent models Get e-Alerts