Optimal waiting period for foot salvage surgery following limb revascularization

医学 外科 血运重建 缺血 灌注 充氧 麻醉 脚(韵律) 心脏病学 语言学 哲学 心肌梗塞
作者
Carlos I. Arroyo,Victor G Tritto,Dale Buchbinder,Clifford F. Melick,Richard A Kelton,Joseph M. Russo,Wade A Ritter,Chris P Kassaris,Michael S Presti
出处
期刊:Journal of Foot & Ankle Surgery [Elsevier BV]
卷期号:41 (4): 228-232 被引量:18
标识
DOI:10.1016/s1067-2516(02)80019-9
摘要

It is not clear how soon after bypass surgery tissue perfusion in the ischemic foot is adequate for healing. The purpose of this study was to determine the time interval for tissue to receive adequate oxygenation for healing following limb revascularization. Eleven patients with severe foot ischemia as defined by a transcutaneous oxygen tension (TcPO2) of 30 mm Hg or less were included in the study. TcPO2 measurements were performed prior to the lower extremity bypass and at postoperative day 1, 2, and 3. The mean preoperative value (9.27 mm Hg) was compared with the mean value at postoperative day 1 (17.73 mm Hg), postoperative day 2 (20.36mm Hg), and postoperative day 3 (36.82 mm Hg) using paired samples t-tests. Statistically significant differences were observed between the mean preoperative TcPO2 measurement and the mean TcPO2 measurement taken on the 3rd postoperative day. The mean TcPO2 level increased from 9.27 mm Hg preoperatively to 36.82 mm Hg by the 3rd postoperative day (p = .001). There was also a statistically significant difference between the mean values on the 2nd (20.36 mm Hg) and 3rd postoperative day (36.82 mm Hg) (p = .002). Despite this finding, 5 of the 11 patients still had individual TcPO2 readings of less than 30 mm Hg on the 3rd postoperative day. Therefore, it can be concluded that in most instances tissue oxygenation reaches an adequate level after waiting at least 3 days following a bypass. Waiting 3 or more days could give adequate time for tissue reperfusion to promote healing of the surgical site. It is not clear how soon after bypass surgery tissue perfusion in the ischemic foot is adequate for healing. The purpose of this study was to determine the time interval for tissue to receive adequate oxygenation for healing following limb revascularization. Eleven patients with severe foot ischemia as defined by a transcutaneous oxygen tension (TcPO2) of 30 mm Hg or less were included in the study. TcPO2 measurements were performed prior to the lower extremity bypass and at postoperative day 1, 2, and 3. The mean preoperative value (9.27 mm Hg) was compared with the mean value at postoperative day 1 (17.73 mm Hg), postoperative day 2 (20.36mm Hg), and postoperative day 3 (36.82 mm Hg) using paired samples t-tests. Statistically significant differences were observed between the mean preoperative TcPO2 measurement and the mean TcPO2 measurement taken on the 3rd postoperative day. The mean TcPO2 level increased from 9.27 mm Hg preoperatively to 36.82 mm Hg by the 3rd postoperative day (p = .001). There was also a statistically significant difference between the mean values on the 2nd (20.36 mm Hg) and 3rd postoperative day (36.82 mm Hg) (p = .002). Despite this finding, 5 of the 11 patients still had individual TcPO2 readings of less than 30 mm Hg on the 3rd postoperative day. Therefore, it can be concluded that in most instances tissue oxygenation reaches an adequate level after waiting at least 3 days following a bypass. Waiting 3 or more days could give adequate time for tissue reperfusion to promote healing of the surgical site.

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
漆漆完成签到 ,获得积分10
刚刚
3秒前
3秒前
蜉蝣完成签到,获得积分10
3秒前
不想看文献完成签到,获得积分10
4秒前
IWJL发布了新的文献求助10
4秒前
Lin完成签到,获得积分10
7秒前
科研通AI2S应助是非采纳,获得10
7秒前
hh完成签到,获得积分10
7秒前
甜叶菊发布了新的文献求助10
8秒前
陶汪酱完成签到,获得积分10
9秒前
冷傲忆彤完成签到 ,获得积分10
9秒前
痴情的机器猫完成签到,获得积分10
10秒前
11秒前
天爱cf完成签到 ,获得积分10
11秒前
13秒前
呱呱乐完成签到,获得积分10
13秒前
elisa828发布了新的文献求助10
14秒前
xx发布了新的文献求助10
15秒前
15秒前
李健的粉丝团团长应助mark采纳,获得10
17秒前
C居完成签到 ,获得积分10
17秒前
18秒前
ommo给ommo的求助进行了留言
19秒前
20秒前
f数字完成签到,获得积分10
20秒前
AA完成签到,获得积分10
21秒前
英姑应助My采纳,获得10
22秒前
沉静胜完成签到,获得积分10
22秒前
23秒前
23秒前
莫三颜发布了新的文献求助10
24秒前
脑洞疼应助科研通管家采纳,获得10
25秒前
斯文败类应助科研通管家采纳,获得20
25秒前
隐形曼青应助科研通管家采纳,获得10
25秒前
Nole应助科研通管家采纳,获得10
25秒前
25秒前
喷火娃应助科研通管家采纳,获得10
25秒前
Kao应助科研通管家采纳,获得10
26秒前
Lucas应助科研通管家采纳,获得10
26秒前
高分求助中
(应助此贴封号)【重要!!请各用户(尤其是新用户)详细阅读】【科研通的精品贴汇总】 10000
Matrix Methods in Data Mining and Pattern Recognition Second Edition 510
Handbuch Trainingswissenschaft – Trainingslehre 500
Additive Manufacturing Design and Applications (ASM Handbook, Volume 24A) 500
Variations: A More Diverse Picture of Contemporary Art 400
A Primer on Partial Least Squares Structural Equation Modeling (PLS-SEM) Fourth Edition 400
Induction Heating and Heat Treatment (ASM Handbook, Volume 4C) 300
热门求助领域 (近24小时)
化学 材料科学 医学 生物 纳米技术 工程类 有机化学 化学工程 生物化学 计算机科学 内科学 物理 复合材料 催化作用 细胞生物学 无机化学 光电子学 物理化学 电极 基因
热门帖子
关注 科研通微信公众号,转发送积分 7586566
求助须知:如何正确求助?哪些是违规求助? 9164896
关于积分的说明 19613398
捐赠科研通 7167062
什么是DOI,文献DOI怎么找? 3266670
关于科研通互助平台的介绍 2431696
邀请新用户注册赠送积分活动 2258456