Optimal waiting period for foot salvage surgery following limb revascularization

医学 外科 血运重建 缺血 灌注 充氧 麻醉 脚(韵律) 心脏病学 语言学 哲学 心肌梗塞
作者
Carlos I. Arroyo,Victor G Tritto,Dale Buchbinder,Clifford F. Melick,Richard A Kelton,Joseph M. Russo,Wade A Ritter,Chris P Kassaris,Michael S Presti
出处
期刊:Journal of Foot & Ankle Surgery [Elsevier BV]
卷期号:41 (4): 228-232 被引量:18
标识
DOI:10.1016/s1067-2516(02)80019-9
摘要

It is not clear how soon after bypass surgery tissue perfusion in the ischemic foot is adequate for healing. The purpose of this study was to determine the time interval for tissue to receive adequate oxygenation for healing following limb revascularization. Eleven patients with severe foot ischemia as defined by a transcutaneous oxygen tension (TcPO2) of 30 mm Hg or less were included in the study. TcPO2 measurements were performed prior to the lower extremity bypass and at postoperative day 1, 2, and 3. The mean preoperative value (9.27 mm Hg) was compared with the mean value at postoperative day 1 (17.73 mm Hg), postoperative day 2 (20.36mm Hg), and postoperative day 3 (36.82 mm Hg) using paired samples t-tests. Statistically significant differences were observed between the mean preoperative TcPO2 measurement and the mean TcPO2 measurement taken on the 3rd postoperative day. The mean TcPO2 level increased from 9.27 mm Hg preoperatively to 36.82 mm Hg by the 3rd postoperative day (p = .001). There was also a statistically significant difference between the mean values on the 2nd (20.36 mm Hg) and 3rd postoperative day (36.82 mm Hg) (p = .002). Despite this finding, 5 of the 11 patients still had individual TcPO2 readings of less than 30 mm Hg on the 3rd postoperative day. Therefore, it can be concluded that in most instances tissue oxygenation reaches an adequate level after waiting at least 3 days following a bypass. Waiting 3 or more days could give adequate time for tissue reperfusion to promote healing of the surgical site. It is not clear how soon after bypass surgery tissue perfusion in the ischemic foot is adequate for healing. The purpose of this study was to determine the time interval for tissue to receive adequate oxygenation for healing following limb revascularization. Eleven patients with severe foot ischemia as defined by a transcutaneous oxygen tension (TcPO2) of 30 mm Hg or less were included in the study. TcPO2 measurements were performed prior to the lower extremity bypass and at postoperative day 1, 2, and 3. The mean preoperative value (9.27 mm Hg) was compared with the mean value at postoperative day 1 (17.73 mm Hg), postoperative day 2 (20.36mm Hg), and postoperative day 3 (36.82 mm Hg) using paired samples t-tests. Statistically significant differences were observed between the mean preoperative TcPO2 measurement and the mean TcPO2 measurement taken on the 3rd postoperative day. The mean TcPO2 level increased from 9.27 mm Hg preoperatively to 36.82 mm Hg by the 3rd postoperative day (p = .001). There was also a statistically significant difference between the mean values on the 2nd (20.36 mm Hg) and 3rd postoperative day (36.82 mm Hg) (p = .002). Despite this finding, 5 of the 11 patients still had individual TcPO2 readings of less than 30 mm Hg on the 3rd postoperative day. Therefore, it can be concluded that in most instances tissue oxygenation reaches an adequate level after waiting at least 3 days following a bypass. Waiting 3 or more days could give adequate time for tissue reperfusion to promote healing of the surgical site.

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
刚刚
雾昂完成签到,获得积分10
1秒前
1111发布了新的文献求助10
1秒前
小可发布了新的文献求助10
1秒前
1秒前
闾丘曼安发布了新的文献求助10
2秒前
3秒前
调皮的吐司完成签到,获得积分10
3秒前
嘛也不会发布了新的文献求助10
4秒前
4秒前
烟花应助wanglihui采纳,获得10
4秒前
提灯发布了新的文献求助10
4秒前
4秒前
4秒前
清爽泥猴桃完成签到,获得积分10
5秒前
赵泰发布了新的文献求助10
5秒前
5秒前
Hello应助eay采纳,获得10
6秒前
courage完成签到,获得积分10
6秒前
6秒前
7秒前
完美世界应助牛有德采纳,获得10
8秒前
夏天发布了新的文献求助10
9秒前
浮光发布了新的文献求助10
9秒前
9秒前
小苦瓜完成签到,获得积分10
9秒前
xieyuanxing完成签到,获得积分20
10秒前
栗子完成签到,获得积分10
10秒前
Mong那粒沙完成签到,获得积分10
10秒前
万能图书馆应助木光采纳,获得10
11秒前
11秒前
ASH应助Katyusha采纳,获得10
12秒前
12秒前
提灯完成签到,获得积分10
12秒前
12秒前
研友_n0kYwL发布了新的文献求助10
12秒前
好久没上微信了完成签到,获得积分10
12秒前
13秒前
13秒前
高分求助中
(应助此贴封号)【重要!!请各用户(尤其是新用户)详细阅读】【科研通的精品贴汇总】 10000
Effects of Two Weeks of Red Light Therapy on Choroidal Thickness and Axial Length in Young Adults 700
Positive Art Therapy Theory and Practice 600
Management and the Arts 510
Matrix Methods in Data Mining and Pattern Recognition Second Edition 510
Key mechanistic insights into the intramolecular C-H bond amination and double bond aziridination in sulfamate esters catalyzed by dirhodium tetracarboxylate complexes 500
The Neuroscience of Language 400
热门求助领域 (近24小时)
化学 材料科学 医学 生物 纳米技术 工程类 有机化学 化学工程 生物化学 计算机科学 内科学 物理 复合材料 催化作用 细胞生物学 无机化学 光电子学 物理化学 电极 基因
热门帖子
关注 科研通微信公众号,转发送积分 7671253
求助须知:如何正确求助?哪些是违规求助? 9238574
关于积分的说明 19896651
捐赠科研通 7240868
什么是DOI,文献DOI怎么找? 3285035
关于科研通互助平台的介绍 2443325
邀请新用户注册赠送积分活动 2287179