增生性瘢痕
伤口愈合
疤痕
成纤维细胞
瘢痕组织
病理
增生性瘢痕
烧伤
等离子体
化学
医学
外科
生物化学
量子力学
物理
体外
作者
Dae Hoon Lee,Jae‐Ok Lee,Wonju Jeon,Ihn-Geun Choi,Jun-Sub Kim,Je Hoon Jeong,Tae‐Cheon Kang,Cheong Hoon Seo
摘要
Suppression of hypertrophic scar generation in an animal model by treatment with plasma is reported. Contact burn following mechanical stretching was used to induce scar formation in mice. Exposure to the plasma tended to reduce the scar area more rapidly without affecting vitality. The treatment resulted in decreased vascularization in the scar tissue. Plasma-treated scars showed mild decrease in the thickness of hypertrophic tissues as shown by histological assessment. Finally, we showed that plasma treatment induced cell death and reactive oxygen species generation in hypertrophic scar fibroblast. All of the results support that plasma treatment can control scar generation.
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