促红细胞生成素肝细胞(Eph)受体
以法林
细胞生物学
受体酪氨酸激酶
EPH受体A2
轴突引导
细胞
信号
生物
细胞粘附
受体蛋白酪氨酸激酶
电池类型
受体
信号转导
轴突
生物化学
摘要
Eph receptor tyrosine kinases mould the behaviour of many cell types by binding membrane-anchored ligands, ephrins, at sites of cell-cell contact. Eph signals affect both of the contacting cells and can produce diverse biological responses. New models explain how quantitative variations in the densities and signalling abilities of Eph receptors and ephrins could account for the different effects that are elicited on axon guidance, cell adhesion and cell migration during development, homeostasis and disease.
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