Photoinduced palladium-catalyzed asymmetric allylic C–H amination

The direct allylic C–H amination of alkenes, especially internal ones, with aliphatic amines remains a major challenge in chemical synthesis. Recently in Science, Gevorgyan et al. reported a robust strategy for this process with photoinduced palladium catalysis, which accommodates different olefin substitution patterns and offers excellent selectivities. The direct allylic C–H amination of alkenes, especially internal ones, with aliphatic amines remains a major challenge in chemical synthesis. Recently in Science, Gevorgyan et al. reported a robust strategy for this process with photoinduced palladium catalysis, which accommodates different olefin substitution patterns and offers excellent selectivities.