3D打印
立体光刻
熔融沉积模型
生物相容性材料
剂型
制造工程
纳米技术
计算机科学
三维打印
医药制造业
生化工程
工艺工程
生物医学工程
材料科学
医学
工程类
机械工程
药理学
作者
Akash Garg,Rutvi Agrawal,Rohitas Deshmukh
标识
DOI:10.2174/1381612829666230228115442
摘要
3D printing in other fields, such as aviation, is quite old, but in the pharmaceutical area, it is an emerging technique. 3D printing is used to formulate various drug delivery systems and dosage forms with complex geometry. It allows large and fast production of products according to the need of the patient. Today, it is the widely used manufacturing technique in the healthcare field for the engineering of tissues and tissue models, production of medicines and medical devices, organ and tissue bioprinting, implant manufacturing, and production of polypills, vaginal rings, orodispersible films, etc. It allows the production of various dosage forms with complex release profiles containing multiple active ingredients. It is used for manufacturing medicines according to the need of individual patients focusing on the concept of personalized medicines. The idea of customized medicines allows change of dosage and design of the product as per individual and with decreased side effects. This review details various techniques of 3D printing used, such as stereolithography, fused deposition modeling, inkjet printing, etc., and applications and dosage forms developed with the latest patents. The significant challenges in the emergence of the 3D printing technique are the involvement of complex combinations to achieve desired properties, and also, the bioprinter involved provides slow and less resolution. The materials prepared by this technique are both biocompatible and printable, due to which additive manufacturing is increasing in the field of medicine.
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