Background: Charcot-Marie-Tooth disease (CMT) is a peripheral neuropathy accompanied by weakness, atrophy, pes cavus, tremor, hearing loss and changes in sensitivity. In Parkinson Disease (PD), patients course with bradykinesia, rigidity, tremor, and postural instability. The presentation of both pathologies in a same individual is rare and cases are related to mutations of the LRSAM1gene.