毛细管电泳
化学
质谱法
背景(考古学)
色谱法
安培法
分析化学(期刊)
电化学
电极
生物
物理化学
古生物学
作者
Martin Koall,Daniel Böhm,Thomas Herl,Frank‐Michael Matysik
标识
DOI:10.1002/elan.202300238
摘要
Abstract In this work, we present the sensitive and selective determination of the widely used insecticide nitenpyram (NIT), utilizing a newly developed dual detection concept (DDC) for capillary electrophoresis (CE). This DDC was realized by combining two complementary detection principles, namely amperometric detection (AD) and mass spectrometry (MS), using a commercially available flow splitter (CE‐AD/MS). The novel DDC was implemented utilizing a newly developed, modular, and user‐friendly CE system with a unique capillary positioning mechanism to improve the workflow. A detailed description of the CE device can be found in the Supporting Information. We investigated the analytical performance of the novel DDC (CE‐AD/MS) in the context of NIT determination. The NIT LOD, obtained by AD, was up to a factor of 14 lower than in case of MS in the context of CE‐AD/MS. The qualitative and quantitative determination of NIT in pharmaceutical samples is presented as a possible application for the novel DDC. Additionally, the oxidation process during AD was examined by hyphenation of electrochemistry to CE‐MS.
科研通智能强力驱动
Strongly Powered by AbleSci AI