Since original data of this study consist of medical records, they are not publicly available due to privacy restrictions. The data that support the findings of this study are available on request from the corresponding author. TABLE S1. Whole exome sequencing statistics and data output. TABLE S2. Immunological profile of the proband. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.