药物警戒
医学
临床试验
替代医学
杠杆(统计)
不利影响
数字健康
叙述性评论
家庭医学
药理学
重症监护医学
医疗保健
病理
政治学
人工智能
法学
计算机科学
作者
Lisa M. Kalisch Ellett,Jack L Janetzki,Renly Lim,Tracey‐Lea Laba,Nicole Pratt
摘要
Pharmacovigilance is defined by the World Health Organization as “the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other medicine/vaccine related problem”. Pharmacovigilance studies are critical for detecting and assessing adverse events of medicines that may not have been observed in clinical trials. This activity is especially important in older people who are often excluded from clinical trials as they have multiple chronic conditions and use multiple medicines for longer durations than the clinical trials. In this narrative review we describe innovative methods in pharmacovigilance studies of medicines in older people that leverage the increasing availability of digital health technologies, electronic health records and real‐world health data to identify and quantify medication related harms in older people.
科研通智能强力驱动
Strongly Powered by AbleSci AI