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Aspirin for prevention of cardiovascular disease in patients with high levels of lipoprotein(a): Evidence from two‐sample Mendelian randomization analysis

医学 内科学 家庭医学 北京 疾病 中国 老年学 政治学 法学
作者
Jiang-Shan Tan,Wei Xu,Jingyang Wang,Tianqi Li,Lu‐Lu Wang,Jun Zhu,Y J Yang
出处
期刊:Journal of Evidence-based Medicine [Wiley]
卷期号:16 (4): 432-434 被引量:1
标识
DOI:10.1111/jebm.12562
摘要

Journal of Evidence-Based MedicineVolume 16, Issue 4 p. 432-434 LETTER Aspirin for prevention of cardiovascular disease in patients with high levels of lipoprotein(a): Evidence from two-sample Mendelian randomization analysis Jiang-shan Tan, Jiang-shan Tan Emergency Center, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease of China, National Center for Cardiovascular Diseases, National Clinical Research Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaSearch for more papers by this authorWei Xu, Wei Xu Emergency Center, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease of China, National Center for Cardiovascular Diseases, National Clinical Research Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaSearch for more papers by this authorJingyang Wang, Jingyang Wang Emergency Center, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease of China, National Center for Cardiovascular Diseases, National Clinical Research Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaSearch for more papers by this authorTianqi Li, Tianqi Li Key Laboratory of Pulmonary Vascular Medicine, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, ChinaSearch for more papers by this authorLulu Wang, Lulu Wang Emergency Center, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease of China, National Center for Cardiovascular Diseases, National Clinical Research Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaSearch for more papers by this authorJun Zhu, Jun Zhu Emergency Center, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease of China, National Center for Cardiovascular Diseases, National Clinical Research Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaSearch for more papers by this authorYanmin Yang, Corresponding Author Yanmin Yang [email protected] orcid.org/0000-0002-6863-5585 Emergency Center, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease of China, National Center for Cardiovascular Diseases, National Clinical Research Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China Correspondence Yanmin Yang, Emergency Center, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease of China, National Center for Cardiovascular Diseases, National Clinical Research Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China. Email: [email protected]Search for more papers by this author Jiang-shan Tan, Jiang-shan Tan Emergency Center, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease of China, National Center for Cardiovascular Diseases, National Clinical Research Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaSearch for more papers by this authorWei Xu, Wei Xu Emergency Center, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease of China, National Center for Cardiovascular Diseases, National Clinical Research Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaSearch for more papers by this authorJingyang Wang, Jingyang Wang Emergency Center, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease of China, National Center for Cardiovascular Diseases, National Clinical Research Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaSearch for more papers by this authorTianqi Li, Tianqi Li Key Laboratory of Pulmonary Vascular Medicine, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, ChinaSearch for more papers by this authorLulu Wang, Lulu Wang Emergency Center, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease of China, National Center for Cardiovascular Diseases, National Clinical Research Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaSearch for more papers by this authorJun Zhu, Jun Zhu Emergency Center, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease of China, National Center for Cardiovascular Diseases, National Clinical Research Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaSearch for more papers by this authorYanmin Yang, Corresponding Author Yanmin Yang [email protected] orcid.org/0000-0002-6863-5585 Emergency Center, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease of China, National Center for Cardiovascular Diseases, National Clinical Research Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China Correspondence Yanmin Yang, Emergency Center, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease of China, National Center for Cardiovascular Diseases, National Clinical Research Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China. Email: [email protected]Search for more papers by this author First published: 04 December 2023 https://doi.org/10.1111/jebm.12562 Jiang-shan Tan and Wei Xu contributed equally to this work. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. REFERENCES 1Li ZG, Li G, Zhou YL, et al. Lack of association between lipoprotein(a) genetic variants and subsequent cardiovascular events in Chinese Han patients with coronary artery disease after percutaneous coronary intervention. Lipids Health Dis. 2013; 12: 127. 10.1186/1476-511X-12-127 PubMedWeb of Science®Google Scholar 2Liu HH, Cao YX, Jin JL, et al. Predicting cardiovascular outcomes by baseline lipoprotein(a) concentrations: a large cohort and long-term follow-up study on real-world patients receiving percutaneous coronary intervention. J Am Heart Assoc. 2020; 9(3), e014581. 10.1161/JAHA.119.014581 PubMedWeb of Science®Google Scholar 3Kamstrup PR. Lipoprotein(a) and cardiovascular disease. Clin Chem. 2021; 67(1), 154–166. 10.1093/clinchem/hvaa247 PubMedWeb of Science®Google Scholar 4Kronenberg F, Mora S, Stroes ESG, et al. Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement. Eur Heart J. 2022; 43(39), 3925–3946. 10.1093/eurheartj/ehac361 CASPubMedWeb of Science®Google Scholar 5Tsimikas S. A test in context: lipoprotein(a): diagnosis, prognosis, controversies, and emerging therapies. J Am Coll Cardiol. 2017; 69(6), 692–711. 10.1016/j.jacc.2016.11.042 CASPubMedWeb of Science®Google Scholar 6O'Donoghue ML, Morrow DA, Tsimikas S, et al. Lipoprotein(a) for risk assessment in patients with established coronary artery disease. J Am Coll Cardiol. 2014; 63(6), 520–527. 10.1016/j.jacc.2013.09.042 PubMedWeb of Science®Google Scholar 7Nestel PJ, Barnes EH, Tonkin AM, et al. Plasma lipoprotein(a) concentration predicts future coronary and cardiovascular events in patients with stable coronary heart disease. Arterioscler Thromb Vasc Biol. 2013; 33(12), 2902–2908. 10.1161/ATVBAHA.113.302479 CASPubMedWeb of Science®Google Scholar 8Clarke R, Peden JF, Hopewell JC, et al. Genetic variants associated with Lp(a) lipoprotein level and coronary disease. N Engl J Med. 2009; 361(26), 2518–2528. 10.1056/NEJMoa0902604 CASPubMedWeb of Science®Google Scholar 9Kamstrup PR, Tybjaerg-Hansen A, Steffensen R, Nordestgaard BG. Genetically elevated lipoprotein(a) and increased risk of myocardial infarction. JAMA. 2009; 301(22), 2331–2339. 10.1001/jama.2009.801 CASPubMedWeb of Science®Google Scholar 10Laschkolnig A, Kollerits B, Lamina C, et al. Lipoprotein(a) concentrations, apolipoprotein(a) phenotypes, and peripheral arterial disease in three independent cohorts. Cardiovasc Res. 2014; 103(1), 28–36. 10.1093/cvr/cvu107 CASPubMedWeb of Science®Google Scholar 11Lacaze P, Bakshi A, Riaz M, et al. Aspirin for primary prevention of cardiovascular events in relation to lipoprotein(a) genotypes. J Am Coll Cardiol. 2022; 80(14), 1287–1298. 10.1016/j.jacc.2022.07.027 CASPubMedWeb of Science®Google Scholar 12Nounu A, Richmond RC, Stewart ID, et al. Salicylic acid and risk of colorectal cancer: a two-sample Mendelian randomization study. Nutrients. 2021; 13(11), 4164. 10.3390/nu13114164 CASPubMedWeb of Science®Google Scholar 13Nitsch D, Molokhia M, Smeeth L, DeStavola BL, Whittaker JC, Leon DA. Limits to causal inference based on Mendelian randomization: a comparison with randomized controlled trials. Am J Epidemiol. 2006; 163(5), 397–403. 10.1093/aje/kwj062 PubMedWeb of Science®Google Scholar Volume16, Issue4December 2023Pages 432-434 ReferencesRelatedInformation

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