化学
芳基
分子间力
铜
催化作用
可见光谱
光化学
组合化学
分子
有机化学
烷基
光电子学
物理
作者
Hao Xu,Xufeng Li,Yifei Wang,Xiuyan Song,Yong Shi,Jian Lv,Daoshan Yang
出处
期刊:Organic Letters
[American Chemical Society]
日期:2024-02-26
卷期号:26 (9): 1845-1850
被引量:3
标识
DOI:10.1021/acs.orglett.4c00017
摘要
The difunctionalization of alkenes using aryl thianthrenium salts as the aryl sources has been reported sporadically. However, the four-component difunctionalization of alkenes on the basis of aryl thianthrenium salts has not been reported thus far and still remains a challenge. Herein, a visible light/copper catalysis-enabled four-component reaction of aryl thianthrenium salts, DABCO·(SO2)2, alkenes, and TMSN3 is presented, which affords a facile approach to β-azidosulfones in good yields with broad substrate scope and excellent functional group tolerance. This strategy indirectly realizes the method for the synthesis of β-azidosulfones through site-selective aryl C–H bond functionalization and alkene difunctionalization. This developed method is an important complement to thianthrenium salts chemistry.
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