Chemical contaminants in the environment have become a growing concern due to their detrimental effects on the ecology and evolution of organisms. Understanding the impacts of these contaminants is crucial for mitigating their consequences and promoting sustainable practices. This study aims to examine the direct and indirect effects of chemical contaminants on organisms, explore their role in driving evolutionary processes, and provide a conceptual framework for understanding the ecological and evolutionary impacts of contaminants. A comprehensive review of existing literature and case studies was conducted to assess the effects of chemical contaminants on organisms at various levels of biological organisation. Chemical contaminants have direct effects on organisms, including physiological disruptions, behavioural changes, and reduced reproductive success. These contaminants also drive evolutionary processes by imposing selective pressures and altering genetic diversity within populations. The effects of chemical contaminants on the ecology and evolution of organisms are far-reaching and multifaceted. It is crucial to develop a conceptual framework that considers the interconnectedness of ecological systems to understand and mitigate the impacts of contaminants. Implementing a chemical strategy for sustainability is vital to safeguarding ecosystems, human health, and promoting a harmonious coexistence with the natural world.