Recent progress in synthesis of nano based liposomal drug delivery systems: A glance to their medicinal applications

脂质体 药物输送 纳米载体 纳米技术 药品 生物相容性 靶向给药 药理学 医学 材料科学 冶金
作者
Abdulbast Ali Khafoor,Ayoub Sabir Karim,S. Mohammad Sajadi
出处
期刊:Results in surfaces and interfaces [Elsevier]
卷期号:11: 100124-100124 被引量:9
标识
DOI:10.1016/j.rsurfi.2023.100124
摘要

The process of providing a pharmaceutical substance with a therapeutic effect in human or animals is known as drug delivery. There are several prospects to detect, treat, and heal of difficult illnesses for the development of nanoparticle-based medicines. A diversity of nanomaterials may be transformed into intelligent systems with discreet medicinal and imaging agents by manipulating their size, shape, surface modification, surface features, and materials employed. Such nanomaterials can show controlled release treatment by delivering medications to particular tissues. Additionally, a number of drug delivery methods based on liposomes have been developed as medical treatments. Improvements in the diagnosis and treatment of illnesses have been facilitated using nanoparticles as a tool. Tailored and extended medication administration based liposomal nanostructures improves patient compliance with less frequent doses while reducing drug-related damage. The most current developments in nanostructures synthesis for drug delivery and treatments with emphasis on liposomes are highlighted in this work. Because of their excellent biocompatibility, biodegradability, and minimal immunogenicity, liposomes are the most widely employed nanocarriers for a variety of hydrophobic and hydrophilic compounds that may be biologically operative. Additionally, liposomes have shown to improve the drug dissolution rate, regulated drug delivery, and ability to modify their surface. Liposomes have developed from traditional and immunological liposomes to stimuli-responsive and actively targeted liposomes based on their formation. To treat a variety of disorders, various liposomal-based drug delivery systems are presently medically licensed; therefore, in this review, the structure, content, production techniques, and some therapeutic uses of liposomes are addressed.

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