Association between life’s essential 8 and periodontitis in U.S. adults

牙周炎 全国健康与营养检查调查 医学 内科学 混淆 临床附着丧失 人口学 人口 环境卫生 社会学
作者
Xiangliang Liu,Yuguang Li,Hongyi Wang,Yao Wang,Wei Song,Lin Jia,Wěi Li,Jiuwei Cui
出处
期刊:Scientific Reports [Nature Portfolio]
卷期号:14 (1)
标识
DOI:10.1038/s41598-024-82195-z
摘要

Periodontitis is closely related to lifestyle habits. Our objective was to examine the relationship between the Life's Essential 8 (LE8) and the prevalence of periodontitis in American adults. This study used data from the 2009–2014 National Health and Nutrition Examination Survey (NHANES). LE8 scores (range 0–100) were measured according to the definition by the American Heart Association (AHA) and were categorized as low (0–49), medium (50–79), and high (80–100). The NHANES database on periodontal health was used to data to determine the prevalence of periodontitis. Multivariate regression models and restricted cubic spline (RCS) models were used to assess correlations. Weighted quantile sum (WQS) regression was used to explore the association of LE8 and its components with periodontitis risk. Stratified analysis and interaction analysis were conducted to assess the consistency of the results. In addition, mediation analyses were performed to investigate the role of systemic inflammation in mediating the association of LE8 with periodontitis risk. Participants with moderate (LE8 score 50–79) and high (LE8 score 80–100) scores had 58% (95% CI 0.43–0.79, P < 0.001) and 55% (95% CI 0.37–0.84, P = 0.010) less periodontitis prevalence, respectively, compared with adults with lower total scores. Among all 8 indicators, nicotine exposure (62.3%), blood glucose (18.2%), sleep heath (8.2%), and blood pressure (7.7%) had the most significant impact on periodontitis. Notably, no statistically significant interactions were observed in all subgroup analyses except age (P for interaction < 0.05), indicating that the protective effect of LE8 on periodontitis was shown to be more pronounced in individuals between 40 and 60 years of age. In addition, neutrophil, white blood cell (WBC), and albumin levels mediated the association between LE8 and periodontitis risk, mediating proportions of 13.3%, 21.4%, and 8.3%, respectively. These findings suggest that poorer LE8 scores increase the risk of periodontitis, which may be partly mediated by systemic inflammation.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
量子星尘发布了新的文献求助10
1秒前
mawenyu完成签到,获得积分10
2秒前
17完成签到,获得积分20
2秒前
高大的水壶完成签到,获得积分10
3秒前
英俊的铭应助wellyou采纳,获得10
5秒前
风中的向卉完成签到 ,获得积分10
8秒前
Mp4完成签到 ,获得积分10
8秒前
凌兰完成签到 ,获得积分10
8秒前
plain完成签到,获得积分10
9秒前
陌上花开完成签到,获得积分10
10秒前
11秒前
fg2477完成签到,获得积分10
12秒前
忙碌的数学人完成签到,获得积分10
12秒前
情怀应助Engen采纳,获得10
12秒前
HJJHJH完成签到,获得积分10
14秒前
Bob发布了新的文献求助10
15秒前
16秒前
17秒前
HJJHJH发布了新的文献求助50
18秒前
JW完成签到,获得积分10
18秒前
wanci应助张参采纳,获得10
19秒前
谦让的西装完成签到 ,获得积分10
20秒前
李演员完成签到,获得积分10
21秒前
fei菲飞完成签到,获得积分10
21秒前
23秒前
Zhaowx完成签到,获得积分10
23秒前
Theprisoners完成签到,获得积分0
23秒前
木子发布了新的文献求助30
23秒前
23秒前
下课了吧完成签到,获得积分10
24秒前
丘比特应助xialuoke采纳,获得10
25秒前
zgt01发布了新的文献求助10
27秒前
linfordlu完成签到,获得积分0
27秒前
清浅发布了新的文献求助10
28秒前
风趣的涵柏完成签到,获得积分10
29秒前
31秒前
Chen完成签到 ,获得积分10
32秒前
33秒前
木樨完成签到,获得积分10
34秒前
科研顺利完成签到,获得积分10
35秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Handbook of Industrial Diamonds.Vol2 1100
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038235
求助须知:如何正确求助?哪些是违规求助? 3575992
关于积分的说明 11374009
捐赠科研通 3305760
什么是DOI,文献DOI怎么找? 1819276
邀请新用户注册赠送积分活动 892662
科研通“疑难数据库(出版商)”最低求助积分说明 815022