Catalytic enantioselective and site-specific Friedel–Crafts alkylation of 4-aminoindoles with β,γ-alkynyl-α-ketoimines for the synthesis of C7-functionalized indoles

CPA-catalyzed asymmetric Friedel–Crafts alkylation of 4-aminoindoles with ketoimines enables the synthesis of chiral C7-functionalized indoles.