医学
克罗恩病
耐火材料（行星科学）
间充质干细胞
临床试验
疾病
瘘管
结直肠外科
内科学
外科
外科肿瘤学
胃肠病学
病理
腹部外科
物理
天体生物学
作者
Alireza Hadizadeh,Reza Akbari-asbagh,Asieh Heirani‐Tabasi,Masoud Soleimani,Parastou Gorovanchi,Nasser Ebrahimi Daryani,Amir Vahedi,Hengameh Nazari,Seyedeh-Parnian Banikarimi,Mahnoosh Abbaszade-Dibavar,Behnam Behboudi,Mohammad Sadegh Fazeli,Mohammad Reza Keramati,Amir Keshvari,Alireza Kazemeini,Haleh Pak,Amir-Reza Fazeli,Foroogh Alborzi Avanaki,Seyed Mohsen Ahmadi Tafti
出处
期刊：Diseases of The Colon & Rectum
[Ovid Technologies (Wolters Kluwer)]
日期：2024-09-06
标识
DOI：10.1097/dcr.0000000000003502
摘要
Crohn's disease perianal fistulae are often resistant to standard anti-TNF-α therapies. Mesenchymal stem cell (MSC)-derived exosomes are extracellular vesicles that have highly potent anti-inflammatory effects, and the previous phase of this study demonstrated their safety in the treatment of refractory perianal fistulas.
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