锡尔图因
长寿
医学
西妥因1
老年学
NAD+激酶
遗传学
生物
生物化学
基因
下调和上调
酶
标识
DOI：10.1056/nejmra1100831
摘要
In this year's Franklin H. Epstein Lecture, Leonard Guarente summarizes the many biologic properties of the sirtuin family of deacetylases and explains why enhancement or inhibition of specific sirtuins may influence many common diseases and longevity.
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