The influence of thermal barrier coatings with different thicknesses on turbine blade with internal cooling was investigated using the numerical computation method of conjugate heat transfer.The results show that the temperature of the turbine blade with thermal barrier coatings decreases demonstrably,and the decrease of temperature got much more when approaching to the leading face.The falling speed was slower with the creasing of the thickness of thermal barrier coatings.The leading face has the largest decrease of temperature which was 160K when the thickness of thermal barrier coatings was 0.35mm.