Study on the alkaloids from the stem of Zanthoxylum dissitum

OBJECTIVE To study the alkaloids from the stems of Zanthoxylum dissitum. METHODS Added ammonia to the 0.5% HCl extract solution of the plants until the pH was 11 to collect the total alkaloids. Using the chromatography of alumina and silica gel to separate the alkaloids. According to the physicochemical properties and spectral analysis to elucidate the structures of the constitutes. RESULTS Four compounds were isolated and identified as nitidine (I), sanguinarine (II), zanthobungeanine (III), dictamnine (IV). CONCLUSION Besides dictamnine, three others are isolated from the rhizome of the plant for the first time.