Drawing from the work–home resources model, we examined the relations of family incivility, counterproductive work behaviors (CWB), state self-esteem, and emotional regulation. Results from three-wave lagged data (N = 284) indicated that family incivility was positively correlated with counterproductive work behaviors, and this relationship was mediated by state self-esteem. In addition, emotional regulation mitigated the relationship between family incivility and state self-esteem. The findings suggested that family incivility, as an emotional contextual demand in the home domain, is related to negative outcome (deviant behavior) in the work context (i.e., CWB) through the depletion of the personal resource—state self-esteem, while emotional regulation is a key resource that mitigates this relationship. This paper discusses the implications of these findings with respect to applications and developments of the work–home resources model.