Public resources and services (e.g., datasets, training platforms, pre-trained models) have been widely adopted to ease the development of Deep Learning-based applications. However, if the third-party providers are untrusted, they can inject poisoned samples into the datasets or embed backdoors in those models. Such an integrity breach can cause severe consequences, especially in safety- and security-critical applications. Various backdoor attack techniques have been proposed for higher effectiveness and stealthiness. Unfortunately, existing defense solutions are not practical to thwart those attacks in a comprehensive way.