Sleep Disturbance in School-Aged Children with Atopic Dermatitis: Prevalence and Severity in a Cross-Sectional Sample

睡眠障碍 置信区间 医学 横断面研究 优势比 神经认知 特应性皮炎 人口学 儿科 睡眠(系统调用) 流行病学 内科学 精神科 认知 病理 社会学 皮肤病科 操作系统 计算机科学
作者
Anna B. Fishbein,Brian T. Cheng,Caroline Tilley,Wendy Smith Begolka,Adam C. Carle,Christopher B. Forrest,P. Zee,Amy S. Paller,James W. Griffith
出处
期刊:The Journal of Allergy and Clinical Immunology: In Practice [Elsevier BV]
卷期号:9 (8): 3120-3129.e3 被引量:24
标识
DOI:10.1016/j.jaip.2021.04.064
摘要

Atopic dermatitis (AD) causes sleep disturbance but the epidemiology is not known.To estimate the US prevalence of sleep disturbance and its impact on psychological and neurocognitive function.We conducted a cross-sectional survey of 180 parent-child dyads with AD using stratified sampling based on disease severity (Patient Oriented Eczema Measure: mild [n = 30), moderate (n = 75) or severe (n = 75]), age, and race (White or Black or African American or other). Symptoms of sleep and psychologic health were assessed using the Patient-Reported Outcome Measurement Information System. To estimate the prevalence of sleep disturbance, we calculated weights using poststratification adjustment making marginal frequencies of AD severity, race, and age similar to marginal frequencies in the 2007 National Survey of Children's Health. Unweighted regression models examined associations with sleep disturbance.In children age 5 to 17 years with AD, we estimated that sleep disturbance occurred in 66.9% (95% confidence interval, 53.3% to 80.5%; 3,116,305 children). The odds of severe sleep disturbance (worse than 95% of US children) were highest in moderate to severe versus mild AD (2.03 [1.00-4.10]; P = .0495; compared with 8.68 [1.82-41.49]; P = .0068). Predictors of parent proxy-reported sleep disturbance were itch intensity (adjusted β [95% confidence interval] 1.33 [0.62-2.04]) and low income (<$50,000: 6.64 [2.05-11.23]; and $50,000 to less than 100,000: 4.75 [0.35-9.14]). Controlling for disease severity, itch intensity, and significant sociodemographics-parent-proxy, reported sleep disturbance was associated with increased severity of sleep-related impairment, depression, fatigue, and anxiety, in addition to worse inattention and impulsivity. In fully adjusted models, children who self-reported sleep disturbance (T-score ≥60) had increased odds of sleep-related impairment (1.20 [1.11-1.29]), depression (1.13 [1.03, 1.24]), fatigue (1.28 [1.06-1.54]), and anxiety (1.16 [1.02-1.31]).Sleep disturbance is a common symptom of AD. It affects about 3 million US children and is associated with neuropsychiatric impairment, including depression, anxiety, and inattention. Clinicians should screen for these symptoms in school-aged children, particularly those with moderate to severe AD.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
所所应助过氧化氢采纳,获得10
1秒前
青山发布了新的文献求助50
2秒前
2秒前
大白发布了新的文献求助10
2秒前
2秒前
热情的达完成签到,获得积分10
2秒前
酷波er应助十九岁的时差采纳,获得10
2秒前
gj发布了新的文献求助10
3秒前
Hairee发布了新的文献求助10
3秒前
momo发布了新的文献求助10
7秒前
称心尔曼完成签到,获得积分10
8秒前
10秒前
12秒前
谷蓝完成签到,获得积分10
12秒前
14秒前
希望天下0贩的0应助Hairee采纳,获得10
15秒前
Rondab应助ali采纳,获得30
16秒前
懒羊羊完成签到,获得积分10
16秒前
好吃完成签到,获得积分20
16秒前
好吃发布了新的文献求助10
19秒前
19秒前
20秒前
21秒前
量子星尘发布了新的文献求助10
21秒前
张雯思发布了新的文献求助10
21秒前
fjm完成签到,获得积分10
21秒前
老实雁蓉完成签到,获得积分10
22秒前
fjm发布了新的文献求助10
23秒前
25秒前
微醺小王发布了新的文献求助10
25秒前
27秒前
zhang发布了新的文献求助10
27秒前
qqq发布了新的文献求助10
28秒前
29秒前
李潇潇完成签到 ,获得积分10
30秒前
Ava应助笑点低方盒采纳,获得10
30秒前
31秒前
31秒前
胡航航发布了新的文献求助10
33秒前
乖猫要努力应助momo采纳,获得10
34秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989297
求助须知:如何正确求助?哪些是违规求助? 3531418
关于积分的说明 11253893
捐赠科研通 3270097
什么是DOI,文献DOI怎么找? 1804884
邀请新用户注册赠送积分活动 882087
科研通“疑难数据库(出版商)”最低求助积分说明 809158