医学
腰围
体质指数
甘油三酯
接收机工作特性
内科学
2型糖尿病
肥胖
腰高比
优势比
逻辑回归
糖尿病
内分泌学
胆固醇
作者
Pan Ke,Xia Wu,Minzhi Xu,Jie Feng,Hong‐Bin Xu,Yong Gan,Chao Wang,Zhenyu Deng,Xiang Liu,Wenning Fu,Qingfeng Tian,Yan He,Lirong Zhong,Heng Jiang,Zuxun Lu
标识
DOI:10.1007/s40519-021-01238-w
摘要
Although a significant proportion of type 2 diabetes mellitus (T2DM) cases arose from normal-weight individuals, studies on indicators of T2DM in normal-weight people are limited. Accordingly, this study aims to investigate the predictive value of obesity indices and triglyceride glucose-related parameters (TyG-related parameters) in T2DM among normal-weight Chinese elderly.A total of 24,215 normal-weight Chinese elderly (age ≥ 60 years) [body mass index-BMI (18.5-23.9 kg/m2)] were included. Obesity indices and triglyceride glucose-related parameters (TyG-related parameters) included waist circumference (WC), waist-to-height ratio (WHtR), visceral adiposity index (VAI), lipid accumulation product (LAP), and TyG-related parameters (TyG, TyG-BMI, TyG-WC, and TyG-WHtR). Multivariate logistic regression analysis was performed to examine the associations between obesity- and TyG-related indices and T2DM. The areas under the curve (AUC) of the receiver-operating characteristic (ROC) curve analyses were used to evaluate and compare the predictive value of the different indices.The prevalence of T2DM was 14.2% in normal-weight individuals. Among the indices, TyG was significantly associated with T2DM among men and women, respectively, (adjusted odds ratio-aOR per SD 3.46; 95% CI 3.23-3.71) and (aOR per SD 3.64; 95% CI 3.43-3.86). Compared with other indices, TyG had the highest AUC value for T2DM in men (AUC: 0.818, 95% CI 0.810-0.825) and women (AUC: 0.824, 95% CI 0.814-0.833).TyG is an effective marker and outperforms other indices when predicting T2DM in the normal-weight Chinese elderly population.Level V: Opinions of authorities, based on descriptive studies, narrative reviews, clinical experience, or reports of expert committees.
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