已入深夜,您辛苦了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!祝你早点完成任务,早点休息,好梦!

A Prospective, Randomized Trial Comparing the Outcomes of Open vs Laparoscopic Partial Nephrectomy

医学 肾切除术 随机对照试验 腹腔镜检查 泌尿科 外科 普通外科 内科学
作者
Giuliano Guglielmetti,Gabriel Carvalho dos Anjos Silva,Guilherme Sawczyn,Gilberto Rodrigues,Leonardo Cardili,Maurício Cordeiro,Luiz Carlos Neves,José Aírton de Freitas Pontes,Arnaldo Fazoli,Arnaldo Coelho,Miguel Srougi,William C. Nahas
出处
期刊:The Journal of Urology [Lippincott Williams & Wilkins]
卷期号:208 (2): 259-267 被引量:22
标识
DOI:10.1097/ju.0000000000002695
摘要

Partial nephrectomy is the standard treatment for renal tumors <7 cm, and the trend toward minimally invasive surgery has increased. However, data that could support its use and benefits are still lacking.We conducted a prospective, randomized controlled trial comparing surgical, functional and oncologic outcomes in patients undergoing open partial nephrectomy (OPN) or laparoscopic partial nephrectomy (LPN). Randomization was 1:1 to OPN or LPN for the treatment of renal tumors <7 cm. The primary endpoint was surgical complications up to 90 days after surgery. Secondary outcomes were comparison of surgical, oncologic and functional results.We randomized 208 patients between 2012 and 2020 (110 with OPN vs 98 with LPN). Operative data showed no differences in operative time, warm ischemia time, estimated blood loss, transfusions or length of hospital stay. Zero ischemia was more frequent in the OPN (35.4% vs 15.5%, p=0.02). OPN was associated with more abdominal wall complications (31.2% vs 13.1%, p=0.004). Regarding oncologic outcomes, no differences were noted. The LPN group had less kidney function reduction at 3 (-5.2% vs -10%, p=0.04; CI 0.09 to 9.46) and 12 months after surgery (-0.8% vs -6.3%, p=0.02; CI 1.18 to 12.95), and a lower rate of downstaging on the chronic kidney disease classification at 12 months (14.1% vs 32.6%, p=0.006).Surgical and oncologic outcomes of LPN were similar to OPN. Minimally invasive surgery may provide better preservation of kidney function. More studies, especially those involving robotic surgery, are necessary to confirm our findings.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
yuko发布了新的文献求助10
刚刚
Nuckylin完成签到 ,获得积分10
3秒前
简称王完成签到 ,获得积分10
10秒前
w_tiger完成签到 ,获得积分10
11秒前
13秒前
圆圆完成签到 ,获得积分10
15秒前
16秒前
HuY完成签到 ,获得积分10
16秒前
丘比特应助望北楼主采纳,获得10
16秒前
大黑完成签到 ,获得积分10
18秒前
零四零零柒贰完成签到 ,获得积分10
18秒前
dllneu发布了新的文献求助10
19秒前
20秒前
microlite完成签到,获得积分10
20秒前
可爱的小桃完成签到,获得积分10
25秒前
Rondab应助为神指路采纳,获得10
27秒前
27秒前
Charon发布了新的文献求助10
28秒前
29秒前
小丑鱼儿完成签到 ,获得积分10
30秒前
漂亮白枫发布了新的文献求助10
33秒前
充电宝应助1234567采纳,获得10
34秒前
jianglidong发布了新的文献求助10
34秒前
Charon完成签到,获得积分10
36秒前
chenjzhuc完成签到,获得积分10
37秒前
40秒前
卡卡东完成签到 ,获得积分10
41秒前
田様应助漂亮白枫采纳,获得10
41秒前
学术完成签到 ,获得积分10
41秒前
42秒前
43秒前
jianglidong完成签到,获得积分10
44秒前
啦某某完成签到,获得积分10
44秒前
望北楼主发布了新的文献求助10
47秒前
dfgrtbddffh发布了新的文献求助10
47秒前
友好胜完成签到 ,获得积分10
50秒前
51秒前
量子星尘发布了新的文献求助10
52秒前
医疗废物专用车乘客完成签到,获得积分10
52秒前
望北楼主完成签到,获得积分10
52秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3976600
求助须知:如何正确求助?哪些是违规求助? 3520674
关于积分的说明 11204422
捐赠科研通 3257298
什么是DOI,文献DOI怎么找? 1798683
邀请新用户注册赠送积分活动 877842
科研通“疑难数据库(出版商)”最低求助积分说明 806595