PEP群易位
生物
细菌
糖
磷酸转移酶
毒力
生物化学
微生物学
运输机
通透性
细胞生物学
基因
遗传学
大肠杆菌
作者
Katharina Pflüger‐Grau,Boris Görke
标识
DOI:10.1016/j.tim.2010.02.003
摘要
In addition to the sugar phosphotransferase system (sugar PTS) dedicated to carbohydrate uptake, many Gram-negative bacteria possess a so-called nitrogen PTS (PTS(Ntr)). Although fulfilling very different functions, both systems can communicate with each other by phosphate exchange. PTS(Ntr) regulates diverse processes implicated in metabolism of nitrogen and carbon, and is essential for virulence in some bacteria. Additionally, it plays a role in potassium homeostasis by regulating the expression and activity of a high- and a low-affinity K(+) transporter, respectively. In this article, we review recent advances in the understanding of the regulatory roles of PTS(Ntr) in various organisms.
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