遗传性血管水肿
医学
C1抑制剂
重组DNA
临床疗效
临床试验
血管性水肿
皮肤病科
随机对照试验
药理学
内科学
生物化学
基因
化学
作者
Avner Reshef,Marc A. Riedl,Dumitru Moldovan,Richard F. Lockey,Vincenzo Montinaro,Daniel Suez,Anurag Relan,Marco Cicardi,Bruce L. Zuraw
标识
DOI:10.1097/01.wox.0000411830.69753.fb
摘要
Background
Recombinant human C1 Inhibitor (rhC1INH) has been approved in Europe for the treatment of acute hereditary angioedema attacks. The efficacy of rhC1INH was demonstrated in 2 randomized-controlled trials. Open-label extension studies, where patients could be treated for subsequent HAE attacks, demonstrated continued efficacy for repeated rhC1INH treatments.
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