The Structures of Four New C19-Diterpenoid Alkaloids from Aconitum forrestii Stapf

From the root extracts of Aconitum forrestii Stapf, we have isolated four new alkaloids: acoforine (6), acoforesticine (8), acoforestine (10) and acoforestinine (14), besides crassicauline A, forestine and yunaconitine. The structures of these alkaloides were determined on the basisi of spectral data and correlation with alkotoids of established structures. The structure and stereochemistry of acoforestine (10) was confirmed by an X-ray crystal structuer determination.