自愈水凝胶
材料科学
体积热力学
沉浸式(数学)
复合材料
化学工程
化学
高分子化学
物理
数学
量子力学
纯数学
工程类
作者
Hiroyuki Kamata,Yuki Akagi,Yuko Kayasuga-Kariya,Ung‐il Chung,Takamasa Sakai
出处
期刊:Science
[American Association for the Advancement of Science (AAAS)]
日期:2014-02-21
卷期号:343 (6173): 873-875
被引量:531
标识
DOI:10.1126/science.1247811
摘要
Optimizing Injectable Hydrogels Injectable hydrogels are showing promise as scaffolds in regenerative medicine because they can be injected in liquid form and transform in situ into the gel state. However, when exposed to ionic solutions, such as those found in the body, hydrogels can increase in volume by a factor of 2, which can weaken the material. Kamata et al. (p. 873 ) added a thermoresponsive component to a hydrogel so that the thermoresponsive component would tend to collapse in shape when heated and counteract the hydrogel's tendency to swell. Indeed, the resulting gel retained its unswollen volume following immersion in a physiological solution and retained its mechanical strength during repeated stretching or compression.
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