The Synthesis of Various 1,6-Disulfide-Bridged D-Hexopyranoses

1,6-Disulfide-bridged derivatives have been prepared for d-gluco-, d-manno-, d-allo-, d-galacto-, and d-talo-pyranose, in the main by the nucleophilic attack of a C6 thiolate onto an anomeric thiosulfonate. The d-gluco disulfide, ‘angyalosan’, was successfully oxidized to a single thiosulfinate.