炎症性肠病
医学
甲氨蝶呤
入射（几何）
疾病
毒性
胃肠病学
肝毒性
炎症性肠病
内科学
光学
物理
作者
Pamela L. Valentino,Peter Church,Prakesh S. Shah,Joseph Beyene,Anne M. Griffiths,Brian M. Feldman,Binita M. Kamath
出处
期刊：Inflammatory Bowel Diseases
[Oxford University Press]
日期：2013-11-26
卷期号：20 (1): 47-59
被引量：47
标识
DOI：10.1097/01.mib.0000436953.88522.3e
摘要
BackgroundMethotrexate (MTX) is an immunomodulator used in pediatric inflammatory bowel disease (IBD) maintenance regimens. However, MTX use is associated with liver toxicity. We aimed to systematically review and meta-analyze the incidence of hepatotoxicity with MTX use among children with IBD.
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