医学
嵌合抗原受体
细胞因子释放综合征
耐火材料(行星科学)
抗原
受体
免疫疗法
免疫学
内科学
免疫系统
生物
天体生物学
作者
Carl H. June,Michel Sadelain
标识
DOI:10.1056/nejmra1706169
摘要
Interview with Dr. Carl June on chimeric antigen receptor therapy. (09:04)Download This review addresses T-cell engineering and synthetic immunity, with a focus on producing durable remissions in patients with treatment-refractory tumors. Toxic effects of chimeric antigen receptor therapies include cytokine release syndrome and neurologic dysfunction.
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