B细胞激活因子
CD19
抗原
医学
嵌合抗原受体
癌症研究
B细胞
淋巴瘤
T细胞
免疫学
抗体
免疫系统
作者
Hong Qin,Zhenyuan Dong,Xiuli Wang,Wesley A. Cheng,Feng Wen,Weili Xue,Han Sun,Miriam Walter,Guo‐Wei Wei,D. Lynne Smith,Xiuhua Sun,Fan Fei,Jianming Xie,Theano I. Panagopoulou,Chun‐Wei Chen,Joo Y. Song,Ibrahim Aldoss,Clarisse Kayembe,Luisa Sarno,Markus Müschen,Giorgio Inghirami,Stephen J. Forman,Larry W. Kwak
出处
期刊:Science Translational Medicine
[American Association for the Advancement of Science (AAAS)]
日期:2019-09-25
卷期号:11 (511)
被引量:74
标识
DOI:10.1126/scitranslmed.aaw9414
摘要
BAFF receptor is a target for CAR T cell therapy of B cell malignancies, circumventing issues with CD19 antigen loss in tumors.
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