生物
基因组编辑
工具箱
计算生物学
DNA
同源(生物学)
基因组
人类基因组
遗传学
计算机科学
程序设计语言
基因
作者
Marek Marzec,Agnieszka Brąszewska-Zalewska,Göetz Hensel
标识
DOI:10.1016/j.tcb.2020.01.004
摘要
Precise and efficient use of genome editing tools are hampered by the introduction of DNA double-strand breaks, donor DNA templates, or homology-directed repair. A recent study expands the genome editing toolbox with the introduction of prime editing, which overcomes previous challenges and introduces insertions, deletions, and all putative 12 types of base-to-base conversions in human cells.
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