Analysis of retinal microvasculature in Fuchs’ uveitis syndrome. Retinal microvasculature in Fuchs’ uveitis

Summary Purpose The objective of this study is to quantitatively analyse the foveal microvasculature in eyes with Fuchs’ Uveitic Syndrome (FUS), or Fuchs’ Heterochromic Iridocyclitis (FHI), by Optical coherence tomography angiography (OCTA). Methods Thirty patients with FUS and 30 healthy volunteer patients (control group) were enrolled in the study. Vascular density (VD) in the superior and deep capillary plexuses (SCP, DCP) were reported and compared between eyes with FUS (FU), fellow eyes (FE) and the control group. Results Foveal VD and parafoveal VDs in all quadrants of the SCP were significantly lower in the FU group than the FE group and normal eyes (P   0.05); however, parafoveal VDs in all quadrants of the DCP were significantly lower in the FU group than in the FE and control eyes (P  Conclusion Fuchs’ Uveitic Syndrome (Fuchs’ Heterochromic Iridocyclitis) affects not only the anterior uvea and vitreous but also the retinal microvasculature. Analysis by OCT-A may enable us to understand the extent of this disease.