特应性皮炎
医学
皮肤病科
局部用药
精密医学
病理
作者
Caroline Meyer Olesen,Ana B. Pavel,Jianni Wu,Daniela Mikhaylov,Ester Del Duca,Yeriel Estrada,James G. Krueger,Ning Zhang,Maja‐Lisa Clausen,Tove Agner,Emma Guttman‐Yassky
标识
DOI:10.1016/j.jaip.2020.08.037
摘要
Atopic dermatitis (AD) is a common inflammatory skin disease, largely characterized by TH2/TH22 polarization with variable TH1/TH17 skewing and epidermal barrier impairment.1 Skin biopsies represent the criterion standard, and have been instrumental in elucidating key AD mechanisms, facilitating rapid therapeutic development.1 These investigations have also highlighted the heterogeneous nature of AD across multiple endotypes, emphasizing the potential of a precision medicine approach in AD disease management.
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