Topical vitamin A: types, therapeutic effects, adverse reactions and delivery systems

Retinoids describe all forms of vitamin A, including naturally and synthetically produced derivatives. Topical retinoids have now been in regular use in dermatology for half a century, and have been used to treat a variety of cutaneous disorders such as hyperpigmentation and photoageing, as well as fine lines and wrinkles ( Biro and Shalita, 1993 ). In this article, the author will describe several types of topical retinoids and highlight their functions relating to the treatment and prevention of photoageing and acne vulgaris.