Antimicrobial polysaccharides obtained from natural sources

With the increase in resistance to conventional antibiotics among bacterial pathogens, the search for new antimicrobials becomes more and more necessary. Although most studies focus on the discovery of antimicrobial peptides for the development of new antibiotics, several others in the literature have described polysaccharides with the same biological activity with the potential for use as therapeutic alternatives. Here we review the currently available literature on antimicrobial polysaccharides isolated from different sources to demonstrate that there are several possible unconventional carbohydrate polymers that could act as therapeutic alternatives in the battle against drug-resistant pathogens.