Cooperative palladium-catalyzed P(NEt2)3-mediated (4 + 1) annulation of isatins with 2 hydroxymethylallylcarbonates

Cooperative palladium-catalyzed and P(NEt 2 ) 3 -mediated (4 + 1) annulations are developed, leading to a big library of spirooxindole derivatives in high structural diversity.