Prediction of mortality and morbidity with a 6-minute walk test in patients with left ventricular dysfunction. SOLVD Investigators

医学 射血分数 心脏病学 内科学 逻辑回归 心力衰竭 前瞻性队列研究 队列 队列研究
作者
Vera Bittner
出处
期刊:JAMA [American Medical Association]
卷期号:270 (14): 1702-1707 被引量:617
标识
DOI:10.1001/jama.270.14.1702
摘要

Objective.

—To study the potential usefulness of the 6-minute walk test, a self-paced submaximal exercise test, as a prognostic indicator in patients with left ventricular dysfunction.

Design.

—Data were collected during a prospective cohort study, the Studies of Left Ventricular Dysfunction (SOLVD) Registry Substudy.

Setting.

—Twenty tertiary care hospitals in the United States, Canada, and Belgium.

Participants.

—A stratified random sample of 898 patients from the SOLVD Registry who had either radiological evidence of congestive heart failure and/or an ejection fraction of 0.45 or less were enrolled in the substudy and underwent a detailed clinical evaluation including a 6-minute walk test. Patients were followed up for a mean of 242 days.

Outcome Measures.

—Mortality and hospitalization.

Results.

—During follow-up, 52 walk-test participants (6.2%) died and 252 (30.3%) were hospitalized. Hospitalization for congestive heart failure occurred in 78 participants (9.4%), and the combined endpoint of death or hospitalization for congestive heart failure occurred in 114 walk-test participants (13.7%). Compared with the highest performance level, patients in the lowest performance level had a significantly greater chance of dying (10.23% vs 2.99%;P=.01), of being hospitalized (40.91% vs 19.90%;P=.002), and of being hospitalized for heart failure (22.16% vs 1.99%;P<.0001). In a logistic regression model, ejection fraction and distance walked were equally strong and independent predictors of mortality and heart failure hospitalization rates during follow-up.

Conclusion.

—The 6-minute walk test is a safe and simple clinical tool that strongly and independently predicts morbidity and mortality in patients with left ventricular dysfunction. (JAMA. 1993;270:1702-1707)
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
Mason完成签到,获得积分10
刚刚
yizhe发布了新的文献求助10
刚刚
JamesPei应助zzzz采纳,获得10
1秒前
英俊的铭应助aa采纳,获得30
1秒前
xiaohuhuan完成签到,获得积分10
1秒前
bulingbuling完成签到 ,获得积分10
2秒前
一颗小纽扣完成签到,获得积分10
3秒前
席涑完成签到,获得积分10
4秒前
CipherSage应助拼搏的婷冉采纳,获得10
4秒前
luoluo完成签到 ,获得积分10
5秒前
5秒前
醋炒栗子仁完成签到,获得积分10
5秒前
墨尔根戴青完成签到,获得积分10
6秒前
瑾瑜完成签到,获得积分10
7秒前
文小杰完成签到,获得积分10
7秒前
山月完成签到,获得积分10
8秒前
CodeCraft应助研友_LOK59L采纳,获得10
8秒前
8秒前
9秒前
欣慰妙海完成签到 ,获得积分20
9秒前
CodeCraft应助zhaopeipei采纳,获得10
9秒前
LIUYONG发布了新的文献求助10
10秒前
lin发布了新的文献求助10
12秒前
13秒前
九湖夷上完成签到 ,获得积分10
13秒前
噼里啪啦完成签到 ,获得积分10
14秒前
大个应助hahaha123213123采纳,获得30
14秒前
14秒前
惊天大幂幂完成签到,获得积分10
14秒前
英姑应助Fang Xianxin采纳,获得10
15秒前
宋老师发布了新的文献求助30
15秒前
王洋完成签到,获得积分10
16秒前
lw777完成签到,获得积分20
16秒前
慢慢完成签到,获得积分10
16秒前
17秒前
靖123456发布了新的文献求助10
17秒前
拓跋箴完成签到,获得积分10
17秒前
彭于晏应助zy采纳,获得10
18秒前
精明玲完成签到 ,获得积分10
19秒前
19秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
Research on Disturbance Rejection Control Algorithm for Aerial Operation Robots 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038388
求助须知:如何正确求助?哪些是违规求助? 3576106
关于积分的说明 11374447
捐赠科研通 3305798
什么是DOI,文献DOI怎么找? 1819322
邀请新用户注册赠送积分活动 892672
科研通“疑难数据库(出版商)”最低求助积分说明 815029