生物
载脂蛋白E
疾病
没有人
基因
遗传学
风险因素
细胞
生物信息学
内科学
计算机科学
医学
操作系统
作者
Garam Kım,Aaron D. Gitler
出处
期刊：Cell
[Cell Press]
日期：2022-06-01
卷期号：185 (13): 2201-2203
标识
DOI：10.1016/j.cell.2022.05.028
摘要
The ε4 variant in the APOE gene is the strongest genetic risk factor for Alzheimer's disease. How does this gene impact different cell types in the brain to increase disease risk? In this issue of Cell, TCW and colleagues report APOE-driven cell-type-specific changes that may contribute to Alzheimer's disease risk.
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