作者
Aurore Delvenne,Johan Gobom,Betty M. Tijms,Isabelle Bos,Lianne M. Reus,Valerija Dobričić,Mara ten Kate,Frans R.J. Verhey,Inez H.G.B. Ramakers,Philip Scheltens,Charlotte E. Teunissen,Rik Vandenberghe,Jolien Schaeverbeke,Silvy Gabel,Julius Popp,Christopher Clark,Pablo Martínez‐Lage,Mikel Tainta,Magda Tsolaki,Yvonne Freund‐Levi,Simon Lovestone,Johannes Streffer,Frederik Barkhof,Lars Bertram,Kaj Blennow,Henrik Zetterberg,Pieter Jelle Visser,Stephanie J.B. Vos
摘要
Suspected non-Alzheimer's disease pathophysiology (SNAP) is a biomarker concept that encompasses individuals with neuronal injury but without amyloidosis. We aim to investigate the pathophysiology of SNAP, defined as abnormal tau without amyloidosis, in individuals with mild cognitive impairment (MCI) by cerebrospinal fluid (CSF) proteomics.