Gender-linked differences in human skin

Background The physiology of body organs can be affected by gender. Skin and skin appendages are influenced by sex hormones. Objective This review work has been undertaken to point out the most conspicuous physiological differences observed between men's and women's skin. Methods The literature has been searched and relevant results have been gathered. Results Men's and women's skins differ in hormone metabolism, hair growth, sweat rate, sebum production, surface pH, fat accumulation, serum leptins, etc. Examples of differences in the proneness to cutaneous diseases and skin cancer are quoted. Conclusion The knowledge of gender-linked cutaneous differences might help in preparing male-specific products for more appropriate dermatological treatments or cosmetic interventions.