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Mortality After Elective Abdominal Aortic Aneurysm Repair

医学 腹主动脉瘤 围手术期 队列 择期手术 死亡率 外科 糖尿病 动脉瘤 内科学 内分泌学
作者
Felix J.V. Schlösser,Ilonca Vaartjes,Geert J. M. G. van der Heijden,Frans L. Moll,Hence J.M. Verhagen,Bart E. Muhs,Gert J. de Borst,Andreas T. Tiel Groenestege,J. W. P. F. Kardaun,Agnes de Bruin,Johannes B. Reitsma,Yolanda van der Graaf,Michiel L. Bots
出处
期刊:Annals of Surgery [Ovid Technologies (Wolters Kluwer)]
卷期号:251 (1): 158-164 被引量:63
标识
DOI:10.1097/sla.0b013e3181bc9c4d
摘要

In Brief Objective: Purpose of this study is to provide detailed age- and gender-specific mortality risks of patients hospitalized for elective AAA repair. Summary Background Data: Whether to perform elective abdominal aortic aneurysm (AAA) surgery is balancing the risks of natural history against the risks of surgical intervention. Literature is lacking mortality risks after elective AAA repair with stratification by both age and gender. Methods: Mortality risks for 28 days, 1 year, and 5 years were derived from a nationwide cohort of patients hospitalized for elective AAA repair in 1997 or 2000. This cohort was formed through linkage of the Hospital Discharge Register with the Dutch Population Register. The relations between demographics, medical history and mortality were studied by Cox regression. Results: A total of 3457 patients were identified; 86% males, mean age 72 ± 8.0 years. Mortality risks after elective AAA repair increased with age: 28-day mortality ranged from 3.3% to 27.1% in men and 3.8% to 54.3% in women, 5-year mortality from 12.9% to 78.1% in men and 24.3% to 91.3% in women. Higher age, congestive heart failure, cerebrovascular disease and diabetes mellitus were independent risk factors for 5-years mortality. Conclusions: Mortality risks after elective AAA repair are strongly age-related. Age, gender, and comorbidities should be taken into account when deciding on surgery. A general threshold of 55 mm for surgery might not be justified for all patients. Detailed perioperative and long-term (5 years) age- and gender-specific mortality risks of 3457 patients hospitalized for elective abdominal aortic aneurysm repair were obtained through linkage of national registries. Mortality risks were strongly age and gender related. A general threshold of 55 mm for surgery may not be justified for certain subgroups of patients and might need reconsideration.

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