A common disorder encountered by healthcare specialists is carpal tunnel syndrome (CTS). CTS is a neuropathy disorder caused by compression on the median nerve.Currently, there are several treatment methods for CTS such as: (1) non-steroidal anti-inflammatory drugs (NSAIDs); (2) injection of medications; (3) immobilization by splinting; (4) rehabilitation modalities (therapeutic ultrasound, ASTM AdvantEDGE, stretching and strengthening); and (5) surgery by carpal tunnel release.While NSAIDs, injections, and splinting have shown promise in relieving symptoms, long-term outcomes have been poor.This article provides a background in current treatment methods and an insight into the focal point of the future.