口腔粘膜下纤维性变
癌前状态
医学
纤维化
结缔组织
口腔粘膜
病理
上皮
皮肤病科
胃肠病学
内科学
癌症
作者
J. J. Pindborg,Satyavati M. Sirsat
标识
DOI:10.1016/0030-4220(66)90367-7
摘要
On the basis of the literature and personal experience, we have discussed a pcculiar oral disease—submucous fibrosis—seen mainly among East Indians. The condition is chronic and is clinically characterized by blanching and stiffness of the oral mucosa. Histologically, the oral connective tissue becomes hyalinized and the overlying epithelium markedly atrophic. The disease may be due to an irritant (chili?), acting over a long period of time. Evidence is presented that submucous fibrosis may be considered an important precancerous condition in Southeast Asia.
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