医学
化疗
体外
癌症
肿瘤细胞
肿瘤科
疾病
药品
抗药性
癌症干细胞
癌症研究
内科学
药理学
生物
生物化学
微生物学
标识
DOI:10.1056/nejm198301203080310
摘要
One of the primary goals in caring for patients with malignant disease is to provide a treatment program that maximizes the chance of survival and minimizes the side effects of therapy. This goal is particularly important in chemotherapy for cancer.In 1978, Salmon and colleagues1 reported a new in vitro test for determining the sensitivity or resistance of an individual patient's tumor to an anticancer drug. To perform the test, now called the human tumor stem-cell assay, tumor is removed from the patient, made into a suspension of single cells, exposed to the anticancer drug in vitro, and then cultured . . .
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