Chemo-Re-Irradiation and Salvage Surgery for Locally Recurrent Rectal Cancer

医学 外科肿瘤学 抢救性手术 结直肠癌 普通外科 结直肠外科 外科 肿瘤科 癌症 放射治疗 内科学 腹部外科
作者
Paul B. Romesser,Christopher H. Crane
出处
期刊:Annals of Surgical Oncology [Springer Science+Business Media]
卷期号:28 (9): 4769-4771 被引量:3
标识
DOI:10.1245/s10434-021-10198-5
摘要

2][3][4] Pelvic tumor control and overall survival rates for recurrent rectal cancer are poor with surgery alone.If there is concern for close or positive margins, pelvic re-irradiation may be offered.Intraoperative radiation therapy is also an option at some centers, which may decrease the risk of local tumor recurrence. 5,6n this issue of Annals of Surgical Oncology, Dijkstra et al. reported on the safety and feasibility of (re)-irradiation in patients with recurrent rectal cancer previously treated with surgery ± pelvic irradiation. 7Patients with recurrent rectal cancer treated with salvage surgery were identified, and outcomes were compared between patients treated with prior pelvic radiation (re-irradiation cohort) and radiation-naı ¨ve patients (chemoradiation cohort).All patients were treated with daily conventional fractionated three-dimensional (3D) conformal radiation therapy and concurrent radiation-sensitizing capecitabine.Radiationnaı ¨ve patients were treated with 50 Gy (n = 26), whereas re-irradiation patients were treated with an attenuated dose of 30 Gy (n = 35).Surgical resection was approximate-ly12 weeks post completion of chemoradiation, and intraoperative radiation was permitted if there was concern for a close or positive surgical margin.There were no
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
充电宝应助优秀的凌波采纳,获得10
刚刚
Lenacici发布了新的文献求助10
刚刚
wonder123发布了新的文献求助10
2秒前
Rainnnn完成签到,获得积分10
3秒前
3秒前
麦子发布了新的文献求助10
5秒前
秋白完成签到 ,获得积分10
7秒前
wanci应助家伟采纳,获得10
7秒前
9秒前
情怀应助杜兰特采纳,获得20
9秒前
9秒前
bbh发布了新的文献求助30
10秒前
冷静的无颜完成签到,获得积分10
10秒前
Maxine完成签到 ,获得积分10
10秒前
搜集达人应助qls123采纳,获得10
10秒前
禾苗完成签到 ,获得积分10
12秒前
爆米花应助zhq采纳,获得10
13秒前
13秒前
14秒前
Liufgui应助杨桃采纳,获得10
14秒前
16秒前
congenialboy发布了新的文献求助10
16秒前
yar应助易安采纳,获得30
19秒前
19秒前
家伟发布了新的文献求助10
19秒前
Lucas应助怕孤单的破茧采纳,获得10
20秒前
20秒前
wonder123发布了新的文献求助10
20秒前
大猫应助KK采纳,获得10
20秒前
20秒前
22秒前
微笑的语芙完成签到,获得积分10
23秒前
25秒前
灵巧妙柏发布了新的文献求助10
25秒前
CipherSage应助好滴捏采纳,获得10
26秒前
香云完成签到 ,获得积分10
26秒前
27秒前
搜集达人应助艺涵采纳,获得10
28秒前
M_a完成签到,获得积分10
29秒前
mm驳回了华仔应助
29秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989550
求助须知:如何正确求助?哪些是违规求助? 3531774
关于积分的说明 11254747
捐赠科研通 3270278
什么是DOI,文献DOI怎么找? 1804966
邀请新用户注册赠送积分活动 882125
科研通“疑难数据库(出版商)”最低求助积分说明 809176