Hip Arthroplasty in Patients with Osteogenesis Imperfecta

» Osteogenesis imperfecta (OI) is a rare congenital disorder that affects connective tissue. » Modern medicine has mitigated the mortality that is associated with OI, allowing patients to live a near-normal life span. » The degenerative process in OI is probably accelerated because of subclinical intra-articular fractures, joint laxity, and distorted femoral and acetabular anatomy. » Total hip arthroplasty is seldom performed in patients with OI; it is technically difficult due to bone fragility, deformity, soft-tissue alteration, acetabular protrusion, the risk of intraoperative and postoperative fractures, and joint laxity. » This review highlights that patients with OI need hip arthroplasty procedures at an early age and that early revision surgery can be expected. New-generation uncemented implants may improve implant survivorship.